💉 Injections Instructions for Wegovy and Zepbound
Weekly Subcutaneous Injection Guide
Wegovy and Zepbound are prescription medicines used for chronic weight management. They are given as a once-weekly injection under the skin (subcutaneous). Follow these steps to use Wegovy and Zepbound safely and effectively.
✅ BEFORE YOU BEGIN
| Step | Details |
| 📅 Frequency | Inject once weekly on the same day each week (e.g., every Monday). |
| 📍 Injection Sites | Stomach (abdomen), upper thigh, or upper arm. Rotate sites each week. |
| 🌡️ Storage | Keep in refrigerator (36°F to 46°F / 2°C to 8°C). Can be kept at room temp (up to 86°F/30°C) for up to 28 days. |
| ⏱️ Let it warm up | If refrigerated, let pen sit at room temperature for 30 minutes before injecting. |
💼 SUPPLIES YOU’LL NEED
- Wegovy single-use pen (correct dose)
- Alcohol swab
- Sharps disposal container
🧼 STEP-BY-STEP INJECTION INSTRUCTIONS
1. Wash Your Hands
Use soap and water before handling the pen.
2. Check the Pen
- Confirm the correct dose and expiration date.
- Ensure the medication is clear and colorless (not cloudy or discolored).
- Do not shake the pen.
3. Choose Injection Site
- Preferred areas:
▪ Front of the thighs
▪ Stomach (at least 2 inches away from the navel)
▪ Back of the upper arm (if someone is helping you) - Rotate sites weekly to avoid irritation.
4. Clean the Area
Use an alcohol swab and let the area dry completely.
5. Inject
- Remove the pen cap.
- Place the pen against your skin at a 90-degree angle.
- Press and hold the button until the yellow bar stops moving and you hear two clicks (takes about 5–10 seconds).
- Do not remove the pen until the full dose is delivered.
6. Dispose of Pen
Place the used pen in a FDA-cleared sharps container.
⚠️ IMPORTANT SAFETY TIPS
- Never reuse a Wegovy pen—single use only.
- Do not inject into muscle or vein—only under the skin.
- Skip your dose if more than 5 days late; take your next dose on the regular day.
- Do not share your pen with others.
💡 COMMON SIDE EFFECTS
- Nausea, vomiting, diarrhea, or constipation
- Fatigue or headache
- Injection site redness or swelling
👉 Call your provider if you have severe stomach pain, signs of an allergic reaction, or dehydration.
📞 WHEN TO CALL YOUR HEALTHCARE PROVIDER
- If you accidentally use the wrong dose
- If you miss two or more doses in a row
- If you’re unsure how to inject properly
- If you experience ongoing side effects or unusual symptoms













