Dexilant

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Dexilant (Dexlansoprazole) is a proton-pump inhibitor. It can treat heartburn, gastroesophageal reflux disease (GERD), and esophageal damage.

How should it be used?

  • Take DEXILANT exactly as prescribed by your doctor.
  • Do not change your dose or stop taking DEXILANT without talking to your doctor first.
  • You can take DEXILANT with or without food.
  • Swallow DEXILANT capsules whole. Do not chew DEXILANT capsules or the granules that are in the capsules.
  • If you have trouble swallowing DEXILANT capsules whole, you can open the capsules and sprinkle the contents on a tablespoon of applesauce.
  • If you forget to take a dose of DEXILANT, take it as soon as you remember. If it is almost time for your next dose, do not take the missed dose. Take the next dose on time. Do not take 2 doses at the same time to make up for the missed dose.

Special Precautions/Instructions

Before you take DEXILANT, tell your doctor if you:

  • have been told that you have low magnesium levels in your blood
  • have liver problems
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if DEXILANT will harm your unborn baby.
  • are breastfeeding or planning to breastfeed. It is not known if DEXILANT passes into your breast milk. You and your doctor should decide if you will take DEXILANT or breastfeed. You should not do both. Talk to your doctor about the best way to feed your baby if you take DEXILANT.

Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and herbal supplements. DEXILANT may affect how other medicines work, and other medicines may affect how DEXILANT works.

Especially tell your doctor if you take:

  • an antibiotic that contains ampicillin
  • atazanavir (Reyataz)
  • erlotinib (Tarceva)
  • digoxin (Lanoxin)
  • a product that contains iron
  • ketoconazole (Nizoral)
  • warfarin (Coumadin, Jantoven)
  • tacrolimus (Prograf)
  • methotrexate
  • mycophenolate mofetil (Cellcept)

The most common side effects of DEXILANT include:

  • diarrhea
  • stomach pain
  • nausea
  • common cold
  • vomiting
  • gas

DEXILANT may cause serious side effects, including:

  • Vitamin B12 deficiency
  • Low magnesium levels in your body

Tell your doctor right away if you develop any of these symptoms:

  • Seizures
  • Dizziness
  • abnormal or fast heartbeat
  • jitteriness
  • jerking movements or shaking (tremors)
  • muscle weakness
  • spasms of the hands and feet
  • cramps or muscle aches
  • spasm of the voice box

Storage Conditions

Store DEXILANT at room temperature between 68°F to 77°F (20°C to 25°C).

Emergency/Overdose

Call the national poison control center 1-800-222-1222 or 911 in the event of overdose.

Additional Information

For complete information, please visit: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022287s019lbl.pdf

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