Mesalamine (Lialda) affects a substance in the body that causes inflammation, tissue damage, and diarrhea. Lialda is used to treat ulcerative colitis, proctitis, and protosigmoiditis. It is also used to prevent the symptoms of ulcerative colitis from recurring.

How should it be used?

  • Swallow the tablets whole with a full glass of water.
  • Take with a meal.
  • Do not chew, break or crush the extended release capsule because it is specially made to release after it has passed through your stomach into your intestines.

Special Precautions/Instructions

Tell your doctor about all of the medicines (including over the counter), vitamins, herbal products, and supplements you are taking before you start taking this medicine.

Tell the doctor before you begin taking Lialda if you:

  • Are allergic to sulfasalazine, salicylates or mesalamine
  • Have kidney disease or liver disease
  • Have a stomach blockage
  • Are pregnant, intend to become pregnant or are breastfeeding
  • Are taking non-steroidal anti-inflammatory drugs (NSAIDS)
  • Are taking either of the following medications: axathioprine, 6-mercaptopurine
  • Have a condition predisposing yourself to the development of myocarditis or pericarditis

Side Effects

The most common side effects are headache and flatulence. You may experience side effect symptoms that are similar to the symptoms of UC.

Contact your doctor immediately if you experience cramping, abdominal pain, bloody diarrhea, fever, headache or rash.

Contact your doctor immediately if you experience signs of an allergic reaction including:

  • Diarrhea
  • Feeling sick
  • Fever, shivering/chills, rash
  • Muscle and bone pain
  • Kidney problems (changes in the amount of urine or color of urine)
  • Tiredness, dizziness
  • Itching
  • Swelling
  • Trouble breathing

Storage Conditions

This product should be stored at room temperature away from moisture and heat.


Call the national poison control center 1-800-222-1222 or 911 in the event of overdose. Symptoms of an overdose include vomiting, diarrhea, sore throat, fever, chills, and other signs of infection.

Additional Information

For complete information, please visit:

1975 Town Center Blvd,
Knoxville, TN 37922

Site Map

1975 Town Center Blvd,
Knoxville, TN 37922

Site Map